{"id":16029,"date":"2025-11-14T10:45:42","date_gmt":"2025-11-14T08:45:42","guid":{"rendered":"https:\/\/endocrinesurgeon.gr\/yperthiroidismos\/"},"modified":"2026-01-30T11:26:59","modified_gmt":"2026-01-30T09:26:59","slug":"hyperthyroidism","status":"publish","type":"page","link":"https:\/\/endocrinesurgeon.gr\/en\/hyperthyroidism\/","title":{"rendered":"Hyperthyroidism"},"content":{"rendered":"<p>[vc_row][vc_column][vc_column_text]<\/p>\n<p style=\"text-align: right;\"><a class=\"cmsmasters-icon-print-1\"><span style=\"margin-left: 7px;\">\u0395\u03ba\u03c4\u03cd\u03c0\u03c9\u03c3\u03b7<\/span><\/a><\/p>\n<p>[\/vc_column_text][vc_tta_accordion color=&#8221;sky&#8221; c_icon=&#8221;chevron&#8221; active_section=&#8221;1&#8243; no_fill=&#8221;true&#8221; collapsible_all=&#8221;true&#8221;][vc_tta_section title=&#8221;What Is Hyperthyroidism&#8221; tab_id=&#8221;1615975356574-814f1578-a50b&#8221;][vc_column_text]<b>Hyperthyroidism<\/b><span style=\"font-weight: 400;\"> is a disorder in which the thyroid gland becomes <\/span><b>overactive <\/b><span style=\"font-weight: 400;\">in an uncontrolled manner, disregarding the actual needs of the body. As a result, excessive amounts of thyroid hormones (T3 and T4) are produced, which, through the bloodstream, adversely affect multiple organs and systems of the body.<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><span style=\"font-weight: 400;\">This hypermetabolic state disrupts the normal function of the entire human organism.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Which are the causes of Hyperthyroidism&#8221; tab_id=&#8221;1615975356596-08586a48-adda&#8221;][vc_column_text]<span style=\"font-weight: 400;\">Based on the underlying cause, the main <\/span><b>types of hyperthyroidism <\/b><span style=\"font-weight: 400;\">are the following:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/endocrinesurgeon.gr\/en\/graves-disease\/\"><b>Graves\u2019 disease <\/b><\/a><span style=\"font-weight: 400;\">or toxic diffuse goiter<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Toxic multinodular goiter (Plummer\u2019s disease), in which multiple thyroid nodules produce excessive hormones<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Toxic solitary adenoma, where a single nodule is hyperfunctioning<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Subacute thyroiditis, a transient inflammation of the thyroid gland causing temporary hyperthyroidism<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Iatrogenic (drug-induced) hyperthyroidism, caused by excessive intake of thyroxine or other medications<\/span><\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Which are the symptoms of Hyperthyroidism&#8221; tab_id=&#8221;1769692920061-32d96726-7e30&#8243;][vc_column_text]<span style=\"font-weight: 400;\">The<\/span><b> symptoms <\/b><span style=\"font-weight: 400;\">of hyperthyroidism vary, involve nearly all body systems, and may appear suddenly or gradually. Some of the most common include:<\/span><\/p>\n<ul>\n<li><b>Fatigue, muscle weakness, and easy exhaustion<\/b><\/li>\n<li aria-level=\"1\"><b>Tachycardia, palpitations, or a \u201cfluttering\u201d sensation<\/b><\/li>\n<li aria-level=\"1\"><b>Irritability, nervousness, and anxiety<\/b><\/li>\n<li aria-level=\"1\"><b>Hand tremors<\/b><\/li>\n<li aria-level=\"1\"><b>Increased sweating and heat intolerance<\/b><\/li>\n<li aria-level=\"1\"><b>Sleep disturbances (insomnia)<\/b><\/li>\n<li aria-level=\"1\"><b>Weight changes<\/b><\/li>\n<li aria-level=\"1\"><b>Menstrual irregularities<\/b><\/li>\n<li aria-level=\"1\"><b>Watery stools or diarrhea<\/b><\/li>\n<li aria-level=\"1\"><b>Thyroid enlargement (goiter)<\/b><\/li>\n<li aria-level=\"1\"><b>Eye disorders such as exophthalmos, dryness, blurred vision, or diplopia<\/b><\/li>\n<li aria-level=\"1\"><b>Thin and fragile skin and hair<\/b><\/li>\n<li aria-level=\"1\"><b>Osteopenia, osteoporosis<\/b><\/li>\n<li aria-level=\"1\"><b>Reduced sexual drive<\/b><\/li>\n<li aria-level=\"1\"><b>Low mood or depression<\/b><\/li>\n<li aria-level=\"1\"><b>Severe anxiety and mood fluctuations<\/b><\/li>\n<\/ul>\n<p><b>Mild subclinical hyperthyroidism <\/b><span style=\"font-weight: 400;\">is characterized by low TSH levels, while thyroid hormones FT4 and FT3 remain within normal limits, and it usually <\/span><b>does not<\/b><span style=\"font-weight: 400;\"> present with obvious symptoms.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;How Is Hyperthyroidism Diagnosed&#8221; tab_id=&#8221;1615975445991-abbe6e0b-76e0&#8243;][vc_column_text]<span style=\"font-weight: 400;\">Suspicion for hyperthyroidism arises when some of the above symptoms are present. However, in some cases there are no symptoms, leading to what is known as <\/span><b>latent or subclinical hyperthyroidism.<\/b><\/p>\n<p><b><\/b><span style=\"font-weight: 400;\">Diagnosis is confirmed through blood tests measuring thyroid hormone levels. <\/span><b>A hallmark finding is suppressed thyroid-stimulating hormone (TSH) accompanied by elevated T3 and T4 levels (and their free fractions FT3 and FT4). <\/b><span style=\"font-weight: 400;\">Thyroid autoantibodies are also measured.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Hyperthyroidism and TSH Levels&#8221; tab_id=&#8221;1615975481588-25200828-4edd&#8221;][vc_column_text]<span style=\"font-weight: 400;\">Thyroid-stimulating hormone (<\/span><b>TSH<\/b><span style=\"font-weight: 400;\">) is produced and secreted by the pituitary gland and stimulates the thyroid gland to produce thyroxine (<\/span><b>T4<\/b><span style=\"font-weight: 400;\">) and subsequently triiodothyronine (T3), which affects the metabolism of nearly all body tissues.<\/span><\/p>\n<p><b>Low TSH indicates HYPERTHYROIDISM, while high TSH indicates HYPOTHYROIDISM.<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Normal TSH levels generally range from 0.40 to 4.00 mIU\/L and depend on age, sex, pregnancy, and other factors.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">TSH plays a<\/span><b> critical role <\/b><span style=\"font-weight: 400;\">through the negative feedback mechanism, <\/span><b>regulating metabolism, growth, and energy expenditure. It influences metabolic rate, cardiac function, digestion, muscle control, and brain development.<\/b>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Hyperthyroidism and Body Weight&#8221; tab_id=&#8221;1762173024473-a272b0a5-b2ac&#8221;][vc_column_text]<span style=\"font-weight: 400;\">Hyperthyroidism <\/span><b>accelerates metabolism<\/b><span style=\"font-weight: 400;\">, leading to increased energy consumption and <\/span><b>unintentional weight loss<\/b><span style=\"font-weight: 400;\">, despite increased appetite.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Because<\/span><b> appetite is also increased<\/b><span style=\"font-weight: 400;\">, some patients may not lose weight or may even gain weight, depending on caloric intake.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Hyperthyroidism, Diet, and Aggravating Factors&#8221; tab_id=&#8221;1762173135402-a9a03df8-2900&#8243;][vc_column_text]<span style=\"font-weight: 400;\">Dietary and other factors that should be avoided in hyperthyroidism include:<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><b>Fish, seafood, and shellfish<\/b><\/li>\n<li aria-level=\"1\"><b>Seaweed products and soy products<\/b><\/li>\n<li aria-level=\"1\"><b>Gluten (protein in wheat, barley, rye), nitrates<\/b><\/li>\n<li aria-level=\"1\"><b>Antiseptics and food preservatives<\/b><\/li>\n<li aria-level=\"1\"><b>Exposure to mercury (heavy metals)<\/b><\/li>\n<li aria-level=\"1\"><b>Infections from the herpes virus family (HSV) and Epstein\u2013Barr virus (EBV)<\/b><\/li>\n<li aria-level=\"1\"><b>Certain medications (e.g., the antiarrhythmic drug amiodarone)<\/b><\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Hyperthyroidism and Patient Psychology&#8221; tab_id=&#8221;1615975590436-b57265fb-fab9&#8243;][vc_column_text]<span style=\"font-weight: 400;\">Hyperthyroidism is closely linked to a patient\u2019s <\/span><b>psychological state<\/b><span style=\"font-weight: 400;\">, as it often causes intense symptoms that <\/span><b>significantly affect daily life.<\/b><span style=\"font-weight: 400;\"> These include <\/span><b>anxiety, irritability, nervousness, emotional instability, and persistent unexplained stress.<\/b><\/p>\n<p><b><\/b><span style=\"font-weight: 400;\">Historically, <\/span><b>individuals with Graves\u2019 disease were sometimes mistakenly confined to psychiatric institutions, <\/b><span style=\"font-weight: 400;\">as medical science at the time was unaware of this thyroid disorder and its now readily available treatment.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Hyperthyroidism and Pregnancy&#8221; tab_id=&#8221;1615975556038-9e4b248f-329d&#8221;][vc_column_text]<span style=\"font-weight: 400;\">The autoimmune nature of hyperthyroidism, through hormonal dysfunction, can impair conception and the successful completion of pregnancy. <\/span><b>Surgical treatment often provides a definitive solution for couples wishing to conceive, <\/b><span style=\"font-weight: 400;\">with many achieving pregnancy postoperatively.<\/span><\/p>\n<p><b>Uncontrolled hyperthyroidism during pregnancy<\/b><span style=\"font-weight: 400;\"> carries serious risks, including <\/span><b>miscarriage, preterm delivery, preeclampsia, low birth weight, and cardiac complications <\/b><span style=\"font-weight: 400;\">for both mother and fetus. Additionally, <\/span><b>antithyroid drugs cross the placenta<\/b><span style=\"font-weight: 400;\"> and may cause fetal goiter, hypothyroidism, or neurological complications in the newborn.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Risks of Hyperthyroidism&#8221; tab_id=&#8221;1615976016751-0a946bcb-71fc&#8221;][vc_column_text]<b>Untreated or poorly controlled <\/b><span style=\"font-weight: 400;\">hyperthyroidism may lead to:<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><b>Cardiovascular complications, including atrial fibrillation,<\/b><span style=\"font-weight: 400;\"> which may cause stroke or heart failure<\/span><\/li>\n<li aria-level=\"1\"><b>Arterial hypertension<\/b><\/li>\n<li aria-level=\"1\"><b>Osteoporosis and fractures<\/b><\/li>\n<li aria-level=\"1\"><b>Glucose intolerance, insulin resistance, and hyperinsulinemia<\/b><\/li>\n<li aria-level=\"1\"><b>Menstrual disturbances such as oligomenorrhea or amenorrhea<\/b><\/li>\n<li aria-level=\"1\"><b>Reduced libido, infertility, erectile dysfunction in men, oligospermia, and sterility<\/b><\/li>\n<li aria-level=\"1\"><b>Severe ophthalmopathy: exophthalmos, <\/b><span style=\"font-weight: 400;\">dry eyes, discomfort, photophobia, blurred vision, diplopia, reduced eye mobility<\/span><\/li>\n<li aria-level=\"1\"><b>Thyroid storm (thyrotoxic crisis), <\/b><span style=\"font-weight: 400;\">a life-threatening condition characterized by high fever, severe tachycardia, confusion, and reduced consciousness<\/span><\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;What is the conservative Treatment of Hyperthyroidism&#8221; tab_id=&#8221;1615976104393-438a3c43-b7c5&#8243;][vc_column_text]<span style=\"font-weight: 400;\">Temporary disease remission may be achieved with <\/span><b>antithyroid medications.\u00a0<\/b><\/p>\n<p><span style=\"font-weight: 400;\">These potent drugs (methimazole, carbimazole, propylthiouracil) reduce thyroid hormone production and are typically <\/span><b>administered for 6 to 18 months.<\/b><span style=\"font-weight: 400;\"> Long-term use is discouraged due to risks such as<\/span><b> hepatotoxicity (liver damage)<\/b><span style=\"font-weight: 400;\"> and hematological side effects (<\/span><b>leukopenia<\/b><span style=\"font-weight: 400;\">). Adverse effects may include <\/span><b>rash, hair loss, dizziness, aplastic anemia, lupus-like syndrome, and hepatitis<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Frequent blood tests are required for dose adjustments. <\/span><b>They achieve a temporary remission of the disease, however, as an autoimmune disorder, it may relapse at any time.<\/b><\/p>\n<p><b>Beta-blockers<\/b><span style=\"font-weight: 400;\"> are often prescribed to alleviate symptoms such as arrhythmias, anxiety, muscle weakness, and nervousness. They provide purely <\/span><b>symptomatic relief <\/b><span style=\"font-weight: 400;\">while it is being administered, without curing the underlying disease.<\/span><\/p>\n<p><b>Radioactive iodine<\/b><span style=\"font-weight: 400;\"> is another conservative treatment approach. It involves the administration of radioactivity to the patient with the aim of gradually destroying the hyperfunctioning thyroid cells. This often results in hypothyroidism and the need for lifelong thyroxine replacement therapy. The radioactive energy \u201cablates\u201d the thyroid tissue, however, because the thyroid gland remains in the body, compressive symptoms may still occur, and the risk of malignant transformation, although low, remains present. Radioactive iodine therapy is also frequently associated with worsening of thyroid eye disease. Finally, <\/span><b>the use of radioactive iodine imposes restrictions <\/b><span style=\"font-weight: 400;\">in cases where pregnancy is desired.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In Europe, radioactive iodine therapy is not widely practiced.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Is there a definitive Treatment of Graves\u2019 Disease\u2013Related Hyperthyroidism&#8221; tab_id=&#8221;1763109792028-8d3d20a2-4775&#8243;][vc_column_text]<span style=\"font-weight: 400;\">Today, hyperthyroidism due to Graves\u2019 disease can be treated <\/span><b>safely, definitively, and effectively <\/b><span style=\"font-weight: 400;\">with thyroidectomy.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">It is noteworthy that<\/span><b> the hyperthyroid state, through the psychological disturbances it induces, often prevents the individual from making the decision to pursue a definitive solution to the problem. Unfortunately, the patient may enter a vicious cycle that makes it difficult to reach a rational decision regarding definitive treatment.<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Surgical removal of the thyroid gland <\/span><b>(<a href=\"https:\/\/endocrinesurgeon.gr\/en\/thyroidectomy\/\">thyroidectomy<\/a><\/b><span style=\"font-weight: 400;\">) offers significant advantages over other treatments, including:<\/span><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\">Provides a safe and<\/span><b> definitive cure of the disease, maintaining<\/b><span style=\"font-weight: 400;\"> long-term <\/span><b>therapeutic effectiveness<\/b><\/li>\n<li><span style=\"font-weight: 400;\">Offers a <\/span><b>reduced cardiovascular risk<\/b><span style=\"font-weight: 400;\"> compared with medical therapy<\/span><\/li>\n<li><b>Reduces the incidence of atrial fibrillation <\/b><span style=\"font-weight: 400;\">compared with pharmacological treatment<\/span><\/li>\n<li><b>Decreases the risk of developing diabetes mellitus<\/b><\/li>\n<li><b>Has a comparatively minimal recurrence rate <\/b><span style=\"font-weight: 400;\">when performed by a specialized endocrine surgeon<\/span><\/li>\n<li><b>Eliminates exposure to the adverse effects of potent antithyroid medications, <\/b><span style=\"font-weight: 400;\">which are contraindicated for lifelong use<\/span><\/li>\n<li><b>Relieves the patient from the burden and cost of frequent hormonal testing<\/b><span style=\"font-weight: 400;\"> and repeated endocrinological evaluations<\/span><\/li>\n<li><b>Contributes to avoiding the administration of high doses of radioactivity<\/b><span style=\"font-weight: 400;\"> (I-131 therapy), benefiting both the patient and their close environment<\/span><\/li>\n<li><b>Provides a definitive solution<\/b><span style=\"font-weight: 400;\"> by removing an enlarged thyroid gland that causes <\/span><b>compressive symptoms<\/b><\/li>\n<li><span style=\"font-weight: 400;\">Ensures complete excision of the pathological tissue (which is always subjected to histological examination), thereby <\/span><b>allowing simultaneous removal of coexisting thyroid carcinomas<\/b><\/li>\n<li><b>Definitively corrects hormonal dysfunction<\/b><span style=\"font-weight: 400;\">, freeing the body from the systemic adverse effects of hyperthyroidism across multiple organs and systems<\/span><\/li>\n<li><span style=\"font-weight: 400;\">Finally, <\/span><b>it leads to a remarkable improvement in the psychological disturbances associated with the disease<\/b><\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;What can the patient expect after thyroidectomy for hyperthyroidism&#8221; tab_id=&#8221;1763109834981-6c35c2bb-948e&#8221;][vc_column_text]<span style=\"font-weight: 400;\">Graves\u2019 disease is a treatable condition that can be fully controlled surgically.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In most cases, the <\/span><b>improvement in quality of life is dramatic.<\/b><\/p>\n<p><span style=\"font-weight: 400;\">Postoperatively, patients experience relief from constant tension and anxiety and <\/span><b>regain stable physical and psychological well-being.<\/b><\/p>\n<p><b>Dr. Evangelos Karvounis MD, PhD, FACS<\/b><span style=\"font-weight: 400;\"> is <\/span><b>an award-winning <\/b><a href=\"https:\/\/endocrinesurgeon.gr\/en\/\"><b>endocrine surgeon<\/b><\/a><b>, PhD graduate of the Medical School of Athens, Fellow of the American College of Surgeons, and Director of Endocrine Surgery at Euroclinic of Athens. <\/b><span style=\"font-weight: 400;\">He is available to answer all questions regarding hyperthyroidism and to recommend individualized treatment. <\/span><a href=\"https:\/\/endocrinesurgeon.gr\/en\/contact\/\"><span style=\"font-weight: 400;\">Contact <\/span><\/a><span style=\"font-weight: 400;\">the doctor today by phone or through the contact form to <\/span><b>schedule your appointment for accurate diagnosis and personalized care.<\/b>[\/vc_column_text][\/vc_tta_section][\/vc_tta_accordion][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] \u0395\u03ba\u03c4\u03cd\u03c0\u03c9\u03c3\u03b7 [\/vc_column_text][vc_tta_accordion color=&#8221;sky&#8221; c_icon=&#8221;chevron&#8221; active_section=&#8221;1&#8243; no_fill=&#8221;true&#8221; collapsible_all=&#8221;true&#8221;][vc_tta_section title=&#8221;What Is Hyperthyroidism&#8221; tab_id=&#8221;1615975356574-814f1578-a50b&#8221;][vc_column_text]Hyperthyroidism is a disorder in which the thyroid gland becomes overactive in an uncontrolled manner, disregarding the actual needs of the body. As a result, excessive amounts of thyroid hormones (T3 and T4) are produced, which, through the bloodstream, adversely affect multiple organs and&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-16029","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hyperthyroidism: Causes, Symptoms &amp; Treatment | Karvounis<\/title>\n<meta name=\"description\" content=\"Hyperthyroidism causes excessive thyroid hormone production. 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