{"id":15998,"date":"2025-12-10T15:01:17","date_gmt":"2025-12-10T13:01:17","guid":{"rendered":"https:\/\/endocrinesurgeon.gr\/yperparathireoeidismos\/"},"modified":"2026-01-30T10:35:48","modified_gmt":"2026-01-30T08:35:48","slug":"hyperparathyroidism","status":"publish","type":"page","link":"https:\/\/endocrinesurgeon.gr\/en\/hyperparathyroidism\/","title":{"rendered":"Hyperparathyroidism"},"content":{"rendered":"<p>[vc_row][vc_column][vc_column_text]<\/p>\n<p style=\"text-align: right;\"><a class=\"cmsmasters-icon-print-1\"><span style=\"margin-left: 7px;\">\u0395\u03ba\u03c4\u03cd\u03c0\u03c9\u03c3\u03b7<\/span><\/a><\/p>\n<p>[\/vc_column_text][vc_tta_accordion color=&#8221;sky&#8221; c_icon=&#8221;chevron&#8221; active_section=&#8221;1&#8243; no_fill=&#8221;true&#8221; collapsible_all=&#8221;true&#8221;][vc_tta_section title=&#8221;What Is Hyperparathyroidism&#8221; tab_id=&#8221;1615975356574-814f1578-a50b&#8221;][vc_column_text]<span style=\"font-weight: 400;\">Hyperparathyroidism is a hormonal disorder caused by <\/span><b>excessive production of parathyroid hormone (PTH)<\/b><span style=\"font-weight: 400;\"> by one or more <\/span><a href=\"https:\/\/endocrinesurgeon.gr\/en\/parathyroid\/\"><span style=\"font-weight: 400;\">parathyroid glands<\/span><\/a><span style=\"font-weight: 400;\">. The parathyroid glands are four small glands located behind the thyroid in the neck. Overproduction of PTH leads to <\/span><b>hypercalcemia<\/b><span style=\"font-weight: 400;\"> (elevated calcium levels in the blood), which can cause harmful effects on the bones, kidneys, nervous system, and muscles.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;What Are the Symptoms of Hyperparathyroidism&#8221; tab_id=&#8221;1615975356596-08586a48-adda&#8221;][vc_column_text]<span style=\"font-weight: 400;\">Hyperparathyroidism often remains subtly<\/span><b> asymptomatic<\/b><span style=\"font-weight: 400;\"> for a long period. In more advanced cases, it can cause:<\/span><\/p>\n<ul>\n<li aria-level=\"1\"><b>Fatigue and weakness<\/b><\/li>\n<\/ul>\n<ul>\n<li aria-level=\"1\"><b>Muscle aches and joint pain<\/b><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Depression<\/b><span style=\"font-weight: 400;\">, irritability, and psychological instability<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Kidney stones<\/b><span style=\"font-weight: 400;\"> (nephrolithiasis)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Osteopenia<\/b><span style=\"font-weight: 400;\">, osteoporosis, and spontaneous bone fractures<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Constipation<\/b><span style=\"font-weight: 400;\"> and gastrointestinal disturbances<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">The presence and severity of these symptoms depend on the level of hypercalcemia and the duration of the condition.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;What Are the Types of Hyperparathyroidism&#8221; tab_id=&#8221;1615975445991-abbe6e0b-76e0&#8243;][vc_column_text]<span style=\"font-weight: 400;\">According to ICD-10 classification, hyperparathyroidism is divided into three main types, based on the underlying cause:<\/span><\/p>\n<p><b>A. Primary Hyperparathyroidism<\/b><\/p>\n<p><span style=\"font-weight: 400;\">This is the most common form, caused by an <\/span><b>adenoma <\/b><span style=\"font-weight: 400;\">in one or more parathyroid glands, leading to uncontrolled PTH production and hypercalcemia.<\/span><\/p>\n<p><b>B. Secondary Hyperparathyroidism<\/b><\/p>\n<p><span style=\"font-weight: 400;\">This occurs as a reactive mechanism in response to <\/span><b>chronic kidney disease, vitamin D deficiency, or malabsorption.<\/b><\/p>\n<p><b>C. Tertiary Hyperparathyroidism<\/b><\/p>\n<p><span style=\"font-weight: 400;\">This is a complication of the secondary type, where the parathyroid glands become <\/span><b>permanently overactive.<\/b>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;What Are the Possible Causes of Hyperparathyroidism&#8221; tab_id=&#8221;1615975481588-25200828-4edd&#8221;][vc_column_text]<span style=\"font-weight: 400;\">The causes of hyperparathyroidism may include:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/endocrinesurgeon.gr\/en\/parathyroid-adenoma\/\"><span style=\"font-weight: 400;\">Parathyroid <\/span><b>adenoma<\/b><\/a> <b>(the most common)<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Genetic syndromes<\/b><span style=\"font-weight: 400;\"> (e.g., Multiple Endocrine Neoplasia \u2013 MEN)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Chronic kidney disease<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Long-term vitamin D deficiency<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Disrupted calcium metabolism<\/b><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">In some cases, the disorder may also have a <\/span><b>hereditary component<\/b><span style=\"font-weight: 400;\">.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;How Is Hyperparathyroidism Diagnosed&#8221; tab_id=&#8221;1615975590436-b57265fb-fab9&#8243;][vc_column_text]<b>Until recently, hyperparathyroidism often went<\/b> <b>unnoticed by primary care physicians<\/b><span style=\"font-weight: 400;\">. Today, endocrinologists, with a heightened index of clinical suspicion, can diagnose the condition relatively early and recommend surgical treatment when appropriate.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Mild, often nonspecific symptoms, accompanied by elevated or borderline calcium and parathyroid hormone (PTH) levels in the blood, usually provide the first clues for diagnosis.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Diagnosis is based on a combination of clinical evaluation, laboratory tests, and imaging studies, including:<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Blood tests<\/b><span style=\"font-weight: 400;\"> (Calcium, Parathyroid Hormone, Phosphorus, Vitamin D)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Urine tests<\/b><span style=\"font-weight: 400;\"> (24-hour urine calcium)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Neck ultrasound<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Parathyroid scintigraphy (Sestamibi scan)<\/b><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>DEXA scan<\/b><span style=\"font-weight: 400;\"> (bone density measurement)<\/span><\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;How Is Hyperparathyroidism Treated&#8221; tab_id=&#8221;1615975556038-9e4b248f-329d&#8221;][vc_column_text]<span style=\"font-weight: 400;\">Treatment depends on the type and severity of the condition.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Primary Hyperparathyroidism:<\/b><span style=\"font-weight: 400;\"> Surgical removal of the affected parathyroid gland <\/span><b>(parathyroidectomy)<\/b><span style=\"font-weight: 400;\"> provides a definitive cure.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Secondary Hyperparathyroidism:<\/b><span style=\"font-weight: 400;\"> Management focuses on correcting calcium and vitamin D levels and optimizing kidney function.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Tertiary Hyperparathyroidism:<\/b><span style=\"font-weight: 400;\"> In advanced stages, surgical intervention is recommended.<\/span><\/li>\n<\/ul>\n<p>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Can Hyperparathyroidism Be Treated with Medication&#8221; tab_id=&#8221;1615976016751-0a946bcb-71fc&#8221;][vc_column_text]<span style=\"font-weight: 400;\">Nowadays, there are <\/span><b>medications<\/b><span style=\"font-weight: 400;\"> that can <\/span><b>temporarily reduce calcium levels<\/b><span style=\"font-weight: 400;\"> (though they may have side effects) and are often prescribed by endocrinologists <\/span><b>while awaiting surgery<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In selected cases, patients may receive calcimimetics (e.g., Mimpara, Cinacalcet), vitamin D, or phosphate supplements as needed.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, <\/span><b>medication is not a definitive solution<\/b><span style=\"font-weight: 400;\">. It only provides <\/span><b>temporary symptom control without addressing the underlying cause of the disease.<\/b><span style=\"font-weight: 400;\"> The definitive treatment is the surgical removal of the affected parathyroid gland.<\/span>[\/vc_column_text][\/vc_tta_section][vc_tta_section title=&#8221;Does Hyperparathyroidism Cause Complications&#8221; tab_id=&#8221;1615976104393-438a3c43-b7c5&#8243;][vc_column_text]<span style=\"font-weight: 400;\">Yes, if left <\/span><b>undiagnosed or untreated<\/b><span style=\"font-weight: 400;\">, hyperparathyroidism can lead to serious complications, such as:<\/span><\/p>\n<ul>\n<li><b>Osteoporosis<\/b><span style=\"font-weight: 400;\"> and pathological <\/span><b>fractures<\/b><\/li>\n<li><b>Kidney stones<\/b> or even <b>kidney failure<\/b><\/li>\n<li><b>Cardiovascular complications <\/b>(arrhythmias, hypertension)<\/li>\n<li><b>Cognitive and psychiatric disturbances<\/b><\/li>\n<li><b>Gastric ulcers<\/b><span style=\"font-weight: 400;\"> or pancreatitis<\/span><\/li>\n<\/ul>\n<p><b>Early diagnosis and proper treatment<\/b><span style=\"font-weight: 400;\"> can prevent most of these complications.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">If you are dealing with endocrine <\/span><b>disorders and seeking specialized care, contact Dr. Evangelos Karvounis. Dr. Karvounis, MD<\/b><span style=\"font-weight: 400;\">, PhD, FACS, is an <\/span><b>award-winning <\/b><a href=\"https:\/\/endocrinesurgeon.gr\/en\/\"><b>endocrine surgeon<\/b><\/a><b>, Doctor <\/b><span style=\"font-weight: 400;\">of the Medical School of Athens, and Fellow of the American College of Surgeons. He currently serves as <\/span><b>Director <\/b><span style=\"font-weight: 400;\">of Endocrine Surgery at Euroclinic Athens. <\/span><a href=\"https:\/\/endocrinesurgeon.gr\/en\/contact\/\"><b>Schedule a consultation<\/b><\/a><b> with this highly experienced surgeon<\/b><span style=\"font-weight: 400;\"> for a <\/span><b>scientifically grounded, safe, and effective approach<\/b><span style=\"font-weight: 400;\"> to the treatment of hyperparathyroidism.<\/span>[\/vc_column_text][\/vc_tta_section][\/vc_tta_accordion][\/vc_column][\/vc_row]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] \u0395\u03ba\u03c4\u03cd\u03c0\u03c9\u03c3\u03b7 [\/vc_column_text][vc_tta_accordion color=&#8221;sky&#8221; c_icon=&#8221;chevron&#8221; active_section=&#8221;1&#8243; no_fill=&#8221;true&#8221; collapsible_all=&#8221;true&#8221;][vc_tta_section title=&#8221;What Is Hyperparathyroidism&#8221; tab_id=&#8221;1615975356574-814f1578-a50b&#8221;][vc_column_text]Hyperparathyroidism is a hormonal disorder caused by excessive production of parathyroid hormone (PTH) by one or more parathyroid glands. The parathyroid glands are four small glands located behind the thyroid in the neck. Overproduction of PTH leads to hypercalcemia (elevated calcium levels in the&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-15998","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Hyperparathyroidism: Diagnosis &amp; Surgical Treatment | Karvounis<\/title>\n<meta name=\"description\" content=\"Hyperparathyroidism causes high calcium levels due to excess PTH. 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